After being attacked by a yak in Bhutan, Henry's anthropologist parents decide to send him some place where he can't get himself into any more trouble, Washington, D.C., to live with his uncle and cousin. Upon arrival, he's faced with solving his godfather's murder.
When a mysterious flu-like epidemic sweeps through Smithson High and forces the school into lock down, it's up to our trio of heroes to figure out what's happened before Smithson High becomes the sophomore class's tomb.
A mysterious rock arrives in the DOUM rooms at the NMC, and when Russian mercenaries try to steal it, it's up to Henry, Jasper and Maggie to stop them.
During a car exhibit, Henry finds a letter from John Dillinger to J. Edgar Hoover about a stash of money. The trio go on the hunt for the money to save the school budget cuts and the dean's job.