Inspector Lunge suspects Dr. Tenma in the deaths of three doctors and the disappearance of the Liebert twins; however, he is eventually promoted to chief of surgery. Nine years later, he meets a criminal who warns of an impending monster.
Junkers is interrogated about the murders by Inspector Lunge, and Dr. Tenma persuades him to confess. Junkers flees after discovering his guard has been killed, and Dr. Tenma pursues him.
While Dr. Tenma investigates the serial murders of middle-aged, childless couples and Johan's true identity, law student Nina Fortner receives poetic emails from a stranger.
Dr. Tenma returns to work at a hospital in Dusseldorf, but is forced to flee when the police suspect him of killing an elderly couple in Verden. Meanwhile, Eva pleads with him to take her back.
Dr. Tenma undergoes intense firearms training with a former army veteran named Hugo Bernhardt, who takes care of an orphaned girl after shooting her mother in Myanmar.
While investigating the murder of a prominent councilman and his wife at the Springer Estate in Verden, Tenma encounters the petty criminal Otto Heckel and escapes with him.
Tenma learns that Johan used to be in an orphanage known as Kinderheim 511, where he meets an injured boy named Dieter and a former East German official named Hartmann who used to work there.
Workaholic Inspector Lunge is so focused on his job that he neglects his personal life. When a key suspect in his case commits suicide, he becomes obsessed with catching Tenma. Meanwhile, Eva Heinemann is dissatisfied with her life.
Tenma investigates the Heidelberg murders and learns of a right-wing nationalist organization that's planning to burn down the Turkish portion of Frankfurt. Nina is captured by the organization.
Nina finds Ayse dead at Baby's mansion, where Goedelitz and his men have been killed. Tenma is captured by General Wolf's men, but he sends Dieter to warn the Turkish community.
Nina recalls her time working at an Italian restaurant and taking marksmanship lessons. She learns that her boss, Mr. Rosso, is a former assassin. She leaves to continue her search for Johan.
Tenma visits Dr. Gillen, a former rival, for help in understanding Johan. Dr. Gillen initially turns Tenma over to the authorities, but changes his mind after consulting with a prisoner who provides evidence of Johan's existence.
Braun investigates Karl and Johan after becoming suspicious of their involvement in Farren's death. His investigations lead him to believe that Johan is responsible for a series of murders aimed at isolating Schuwald.
Lunge prioritizes his investigation over his personal life, questioning Tenma's former friends from Japan and discovering a crucial clue related to Johan's fainting spell.
Dr. Reichwein confronts Schuwald about Johan. Reichwein and Lunge both head to the library to stop Johan, while Lotte confronts Nina about her true identity.
Initially suspecting Tenma's involvement in the fire and the planned assassination of Schuwald, Lunge's perspective shifts when Karl asks him to search for Johan. Schuwald tasks Karl with delivering a message to someone in Dresden.
Wolfgang Grimmer, a freelance journalist and former East German, investigates child abuse and psychological reprogramming in former East Germany orphanages.
The Czech police have turned their suspicions towards the journalist Grimmer and the young detective Suk for the murders of their former police chief and three former Czechoslovakian secret police members. Even though he is a suspect, Suk meets with Grimmer to find out the truth.
A Prague police detective from a special investigative team has been killed in Suk's room, and now Suk is being chased as a suspect in a series of murders. Tenma reads about the case in a newspaper...
Nina doesn't know that Johan has disguised himself as her and is confused when people in the street affectionately call her "Anna." Meanwhile, Tenma and Grimmer meet with Captain Karel Lanke, a leader of the former Czechoslovakian secret police.
While searching for the sign with the three frogs, Nina is surprised that she knows the surrounding buildings and streets, but there is a shadow of fear in her memories. Meanwhile, Tenma and Grimmer get an important testimony from Lanke. Inspector Lunge takes a holiday in Prague.
All the orphans who adore Grimmer try to prove his innocence. They find the blonde woman (Johan, disguised as Anna) who was at the scene of the murder.
Inspector Lunge arrives at the Red Rose Mansion after finding a hint in a picture book. Afterwards, he meets with Captainl Lanke, a leader of the former Czechoslovakian secret police.
