When Isadora's fang falls out, she has to decide whether to follow her fairy heritage and give it to the Tooth Fairy or choose the vampire tradition of framing it. She ultimately decides to do what's best for her.
Isadora goes on a school trip to an old castle where she meets a lonely ghost, Oscar, who wants to meet friends but unwittingly scares everyone away. Isadora helps Oscar to interact with her friends, so they accept him for who he is.
When Isadora returns from a weekend at her vampire cousins' she is fired up by all things vampire and rejects her fairy side and accidentally scares away Dad's bats and then shapeshifts into a kitten and can't turn back.
When Isadora agrees to go to Wilbur's Vampire show and Sashi's birthday party at the same time and then realises she can only attend one event, Mirabelle comes up with a magical but flawed plan to help Isadora attend both at once
Isadora tries to use fairy magic to create a birthday present for Mum, but she breaks her wand. It malfunctions and turns Dad bright green. Isadora rushing to fix things doesn't listen to Mignonette's help - with disastrous consequences.
Oscar the ghost makes friends with JJ and wants to learn to play football. But the ball goes straight through him. Isadora and JJ help him realise that even if you are different you can still find a way to make something work for you.
Isadora and Dad see a shooting star fall to earth and when they find it, they realise it's an alien Glow Sprite - Nova, who is searching for her kitten Ganymede. Isadora's family and friends want to help but Nova is mistrustful humans
Isadora's vampire cousin Amma comes for a sleepover. Isadora is anticipating a night of vampire activities, so she is disappointed when Amma only wants to do fairy stuff. The adventure starts when Isadora's grumpiness seeps into her magic.
Isadora is delighted to discover that a tree in the park is being chopped down to make way for a piece of play equipment, but Mum is horrified. Isadora realises Mum is right and wants to find a way to save the tree.
When Isadora's alien friend, Nova the Glow Sprite returns to earth for a play date she is keen to play with Sashi too. Isadora feels jealous when Sashi and Nova delightedly discover all the things they have in common.
Isadora wants to perform ballet at the Vampire Talent Contest, but when she arrives there and realises that the vampires are confused and amused by her choice of an 'unvampirey' act, she loses confidence and decides against it.
Mirabelle persuades Isadora to let her magic up a Glitter Dragon to take to school for Bring Your Pet Day. It causes all sorts of problems when Isadora tries to hide it and causes even more chaos when she takes it into the classroom.
When Isadora tries an aerial vampire move, she tumbles and her confidence is knocked and she doesn't want to fly anymore. Instead of sharing her worry she keeps it to herself. Can she regain the confidence to find her wings once more?
Zoe and Isadora go for a play date at Zoe's annoying cousin Max's house. Zoe begs Isadora to shapeshift into a kitten and pretend to be her pet to impress Max. Isadora agrees but soon regrets it when Zoe gets her doing endless tricks.
Isadora's Aunt Crystal, a winter fairy, brings Isadora's snow friend, Gordy to life. He starts to melt, so they go on an adventure to the land of Snow and Ice where they meet the Snow Queen, ride a snow dragon and find a home for Gordy.
Local celebrity Whippy McFluff decides to film a Ghost Hunting TV show at Isadora's house and Oscar the ghost sees his chance for fame. He prepares a song for his big moment on camera but at the last minute he succumbs to stage fright.
