When Danny Tanners wife tragically dies in a car accident, little does he know that it would change the life of his 3 children, Donna Joe (D.J.), Stephanie and Michelle, and when one dad is not enough, all you need is three.
When Danny Tanner's wife Pamela is killed in an auto accident, he finds himself left all alone to raise his three daughters: D.J., Stephanie, and baby Michelle. Fortunately Danny's hair-obsessed, rock-star brother in-law Jesse Cochran, along with Danny's flamboyant, cartoon loving friend Joey Gladstone, move in to help Danny raise his girls. On the first day, D.J. runs away, and Jesse and Joey find extreme difficulty and anxiety in changing Michelle.
While broadcasting a national fight, Danny lets some information about the fighter's home life slip out that could get him in a lot of trouble. Meanwhile, on the home front Joey and Jesse worry when Michelle develops a cough.
On a stormy night, the family is up telling a bedtime story about a girl that caught the eye of both Jesse and Joey. The girl was being tutored by Jesse, but fell hard for Joey.
While Joey is gone for two weeks on a college tour, the others decide to build him his own bedroom in the garage. Meanwhile, Jesse takes over his duties.
Danny has a important newscast for "Wake up San Fransisco" but Stephanie ends up getting chicken pox along with Jesse And Joey. D.J.(aka Donna Jo) gets invited to a sleepover and ends up babysitting Michelle.
Jesse leaves a note stating he can't take it anymore and wants to get away from the family. Stephanie and D. J. fear he's moving out, so they call and tell him Michelle is really sick so he'll rush home.
Joey's mother gives him an old savings bond. He tries to pay Danny back an eleven-year-old loan, but Danny refuses. Meanwhile, Jesse has a gig as an Elvis impersonator.
