Dr. Tracy, Paul and Jack look after a baby elephant whose mother was killed by poachers. The poachers pretend to be nature photographers and steal the baby elephant.
The owner of a tame lioness brings it to the center when it starts to become aggressive. A farmer threatens to shoot her because he believes she has torn his bold.
A foul-tempered farmer has trained his German shepherd dog to attack any and all animals from the Wameru reserve. Paula and Jack Dane find the animal caught in a poacher's snare, rescue it, and take it back to Dr. Tracy to be treated and, more importantly, re-trained--a prospect that's not likely to sit well with the dog's owner.
Dr. Tracy, Jack, and Mike leave the compound to look for a wounded leopard, not knowing that escaped killer Roy Meadows (seen in the earlier episode "Trail Of The Cheetah") is on the loose with another convict, and headed to Wameru where he plans to have Tracy treat his bullet wound.
With Tracy, Jack, and Mike out in the jungle without their vehicle, Paula is forced to operate on Meadows, speaking to her father over a walkie-talkie for guidance, while her voice teacher and Hedley are also held hostage.
A magazine photographer looking for a story lures a hostile tribe of poachers onto the Wamera reserve, thinking that she will get some "dramatic" pictures to go with the story.
Dr. Tracy treats an injured leopard and releases it into the wild, but a visiting trade commissioner who wants to hunt for big game sets his sights on the leopard for his trophy. Dr. Tracy sets out to derail his plans.
After Dr. Tracy and the Wameru compound are awarded a grant of $75,000 by a wildlife conservation group, two thieves kidnap Judy and Clarence and hold them for ransom to get the money for themselves.
Judy the chimp, who was once bitten by a hyena, gets nervous, scared and agitated when she sees Paul and Jack bring in an injured hyena pup. Dr. Tracy has a difficult time keeping Judy calm enough so he can work on the hyena.
After Hedley warns two hunters to leave the reserve and put out their campfire, one of them starts a fire to drive the rhinos they want to hunt off the reserve and onto legal hunting territory. The fire soon engulfs the reserve, forcing animals to flee, and with Jack and Paula, observing a buffalo herd, in the midst.
Paula and Jack are taken hostage by Connors and Bendix, as the hunters try to escape from the reserve, and from the fire. After they learn that he set the fire, Connors decides that Paula and Jack will have to be killed to keep them quiet.
Visiting archaeologist Dr. Akubar borrows one of the compound's trucks, and Jack as a guide, as he claims to be searching for a legendary hidden treasure. Actually, the doctor and his cohorts are engaging not in an archaeological expedition but a gunrunning operation.
